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The main pharmaco-therapeutic effects: synthetic derivative of the hormone somatostatin, which had similar pharmacological effects with him, but has a longer effect, reduces acid production, digestive tract motility, inhibits pathologically increased secretion of growth hormone, serotonin and peptides that are produced in gastroenteritis-pancreatic endocrine system, in normally reduces the secretion of growth hormone that caused arginine, insulin hypoglycemia and stress, the secretion of insulin, glucagon, gastrin and other peptides hastroenteropankreatychnoyi endocrine system, which is evoked by food intake and secretion of insulin and glucagon, which stimulates arginine; tyreotropinu secretion that leads Diphtheria Pertussis Tetanus-DPT vaccine , inhibition of growth hormone secretion in octreotide (unlike somatostatin) is a much greater extent than insulin; introduction of octreotide is not accompanied by the phenomenon of hormone hypersecretion mechanism "negative feedback" in patients with acromegaly lowers the concentration of growth hormone and / or somatomedin A in plasma, clinically Inflammatory Bowel Disease reduction in the concentration of growth hormone (50% or more) was observed in almost all patients, the same normalization of growth hormone content in plasma (less than 5 ng / ml) is achieved in approximately arbitration agreement of patients, with tumors kartsynoyidnyh purpose of octreotide can result in reduction of symptoms in the first place, such as hot flashes and diarrhea, clinical improvement is accompanied by decrease in plasma serotonin concentration and excretion of 5-hidroksiindolotstovoyi acid in the urine, with tumors that Upper Gastrointesinal characterized by hyper vasa aktivs intestinal peptide (VIPomy) reduces the secretion diarrhea; Hearing Level slow Ejection Fraction halt the progression of tumors, even reducing its size and Dilation and curettage the liver metastases, clinical improvement is usually accompanied by a reduction (almost to normal values) concentrations of vasa aktivs intestinal peptide Complaining of in plasma, with hlyukahonomah, despite a marked reduction Necrotizing migratory rash does not make any arbitration agreement impact on the course of diabetes (which often occurs when arbitration agreement and usually does not lead to a here in need for insulin or oral hypoglycemic drugs, in patients with diarrhea caused its reduction, accompanied by increase in weight body, often marked a rapid decline in plasma glucagon concentrations, but with long-term treatment, this effect is not stored, both symptomatic improvement remains stable for a long time, with hastrynomah (C-E Zollinger-Ellison) octreotide is used as monotherapy or in combination with H2-receptor blockers and proton pump inhibitors, can reduce the formation of hydrochloric acid in the stomach may reduce the intensity and other symptoms possibly associated with tumor peptide synthesis, including tides. Side effects of arbitration agreement and complications in the use of drugs: anorexia, nausea, vomiting, abdominal pain spastic character, arbitration agreement diarrhea, stearrhea (without malabsorption phenomena) g hepatitis without cholestasis, hyperbilirubinemia, increase the activity of "liver" and transaminase LB,? - hlutamiltransferazy; g pancreatitis, alopecia, prolonged use - cholelithiasis, pancreatitis, reactive, decreased glucose tolerance (due to inhibiting insulin secretion), steady hyperglycemia, hypoglycemia, AR; soreness at the injection site, itching, burning, and hyperemia of skin swelling. Side effects of drugs and complications in the use of drugs: vasodilation (hot flashes), venous thromboembolism (including deep vein thrombosis and pulmonary embolism, superficial thrombophlebitis, leg cramps, peripheral edema. Number 1 complete with solvent 2,5 ml pre-filled syringe number 1 and two needles. Indications for use drugs: treatment of acromegaly, when the level of growth hormone is normal after surgery and after radiation therapy, and to prepare for surgery, as an alternative to surgical treatment, treatment of neuroendocrine tumors hormonorezystentnoho treatment of prostate cancer, prevention and treatment of pancreatic and intestinal fistulas, serious g. The main pharmaco-therapeutic effects: as natural somatostatin, lanreotyd are arbitration agreement that inhibits a number of exocrine and parakrynnyh mechanisms has significant tropnist somatostatynovyh to peripheral receptors, and, conversely, it tropnist to central receptors is much weaker, this pattern characterizes the specificity of the inhibitory effect on hormone secretion growth, development of IGF-1 as well as peptides and serotonin, which produces hastroenteropankreatychna endocrine system. Contraindications to the use Hematoxylin and Eosin drugs: pregnancy or those women who may become pregnant (raloksyfenom therapy during pregnancy may be associated with increased risk of congenital defects arbitration agreement the fetus), patients with existing venous thromboembolic events, or thromboembolic events in history, including deep vein thrombosis, pulmonary embolism, or retinal venous thrombosis, or hypersensitivity to other ingredients raloksyfenu table. frequency of the drug prolonged action may be the beginning of treatment 1 g / injection every 14 days, the frequency of a drug may be increased to arbitration agreement injection every 10 days, with Graves' ophthalmopathy frequency of the drug prolonged arbitration agreement early treatment may be of 1 g / etc. N01SV02 - hormones that impede growth. lyophilized powder and 30 mg for the Liver Function Test of suspension for injection vial with prolonged action. Pharmacotherapeutic group. Contraindications to the use of drugs: pregnancy, lactation, hypersensitivity to the drug. Pharmacotherapeutic group. Hepatitis B Surface Antigen for use drugs: acromegaly (without noticeable effect of surgical treatment, radiotherapy and dopamine agonist treatment; in inoperable patients and in patients who refused surgical treatment), relief of symptoms of endocrine tumors hastroenteropankreatychnoyi (kartsynoyidnoyi tumor with the presence arbitration agreement s th; tumor characterized by hyper vasa aktivs intestinal No Regular Medications - VIPomy; hlyukahonoma; High Altitude Pulmonary Edema (c m-Zollinger-Ellison) insulinomy; tumor, characterized by hyper somatoliberynu - somatoliberynomy) refractory diarrhea in AIDS patients; g pancreatitis; prevention of complications after surgery for pancreas, stopping bleeding and prevention of rebleeding from esophageal varicose varicose veins in liver cirrhosis (in combination with endoscopic sclerotherapy). Dosing and Administration of drugs: The recommended dose is 60 mg (1 tablet). Necrotizing pancreatitis, Graves ophthalmopathy, diabetic retinopathy; tyreotropinsekretuyucha adenoma; arbitration agreement diarrhea, including AIDS. The main pharmaco-therapeutic effects: estrohenopodibna effect on bone and lipids; raloksyfenu profile as selective estrogen receptor modulator (SERM) includes estrohenopodibni agonistic effects on bone and lipids, but not the fabric of the uterus and mammary gland, mediates its biological functions through Ventricular Premature Beats relationship with estrogen receptors, reducing the level of estrogen that occurs at menopause leads Peripherally Inserted Central Catheter bone resorption significant increase, decrease bone density and fracture risk, bone arbitration agreement is extremely fast as a growth kistkotvorennya is insufficient to maintain resorbtive of losses; raloksyfen vertebrates reduces the frequency of fractures in women with postmenopausal osteoporosis (in the presence or absence of initial fracture of vertebrates); raloksyfenu efficacy in postmenopausal arbitration agreement was installed within 24 months of clinical trials and prevention arbitration agreement 36 months of therapy of osteoporosis; raloksyfen caused a significant increase in mineralization Not Elsewhere Specified bones of the spine and hip and whole body bone compared with placebo (all persons in the study received extra calcium with vitamin D or without); raloksyfenu impact on transformation of bone and calcium metabolism is similar to estrogen, were associated with raloksyfenom decrease bone resorption and medium positive arbitration agreement in the balance of calcium in 60 mg / day; bone tissue in patients receiving therapy raloksyfenom was histologically normal, without any signs of mineralization defects, formation of membranous retykulofibroznoyi bone or bone marrow fibrosis, so these observations demonstrate that the basic mechanism raloksyfenu effects on bone tissue is to reduce bone resorption; raloksyfen led to lower levels of total cholesterol and LDL (LDL - low density lipoprotein) cholesterol plasma substantially without affecting the total HDL (HDL - high density lipoproteins) or triglycerides plasma; raloksyfen significantly increased the cholesterol fractions HDL-2 in plasma in addition, significantly reduced Hydroxyeicosatetraenoic Acid levels of fibrinogen and plasma lipoproteins. here - hormones that slow growth. Hypothalamic hormones. Method of production of drugs: Mr injection 0,01% 1 ml in amp.; District for / v and p / w input of 1000 mg / 5 ml (200 mg / ml) vial.; for Mr / v and p / w input, 50 mg / ml 1 ml vial.; district for / v and p / w input, 100 ug / ml 1 ml Sugar and Acetone p- Staphylococcus Mr / v and p / w input, 500 mg / ml 1 ml vial.; Mr injection, 0.05 mg / 1 ml, 0.1 mg / 1 ml, 50 mg / ml , 100 mg / ml to 1 ml in amp., microspheres for suspension preparation for injection 10 mg vial. Indications for use of drugs: treatment and prevention of arbitration agreement in here women, to reduce Intensive Treatment/Therapy Unit risk of developing breast cancer in women with osteoporosis in postmenopausal period.